Monday, November 21, 2005

Adult stem cells heal hearts

From Life News:
Adult Stem Cells Derived From Heart Cells Can Repair Heart Damage
Baltimore, MD (LifeNews.com) -- Stem cells derived from human heart tissue develop into multicellular, spherical structures called cardiospheres that express the normal properties of primitive heart tissue, smooth muscle and blood vessel cells, according to a study by Johns Hopkins researchers. In a related study, cells grown in the laboratory from these cardiospheres and injected into the hearts of mice following a lab-induced heart attack migrated straight to damaged tissue and regenerated, improving the organ's ability to pump blood throughout the animal's body. Results from both studies were presented Nov. 14 at the American Heart Association's annual Scientific Sessions in Dallas. "The findings could potentially offer patients use of their own stem cells to repair heart tissue soon after a heart attack, or to regenerate weakened muscle resulting from heart failure, perhaps averting the need for heart transplants," says Eduardo Marbán, M.D., Ph.D., senior author of both studies and professor and chief of cardiology at The Johns Hopkins University School of Medicine and its Heart Institute. "By using a patient's own adult stem cells rather than a donor's, there would be no risk of triggering an immune response that could cause rejection."

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